Liver Carboxylesterase 1 (CES1) (NM_001025194) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC202081L2V

Lenti ORF particles, CES1 (mGFP-tagged) - Human carboxylesterase 1 (CES1), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: CES1
• Synonyms: ACAT; CE-1; CEH; CES2; hCE-1; HMSE; HMSE1; PCE-1; REH; SES1; TGH
• Vector: pLenti-C-mGFP
• ACCN: NM_001025194
• ORF Size: 1947 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202081).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001025194.1, NP_001020365.1
• RefSeq Size: 2024 bp
• RefSeq ORF: 1704 bp
• Locus ID: 1066
• Cytogenetics: 16q12.2
• Protein Families: Druggable Genome
• Protein Pathways: Drug metabolism - other enzymes
• MW: 62.3 kDa
• Gene Summary: 'This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]'