PI3 (NM_002638) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC203136L2V

Lenti ORF particles, PI3 (mGFP-tagged) - Human peptidase inhibitor 3, skin-derived (PI3), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: PI3
• Synonyms: cementoin; ESI; SKALP; WAP3; WFDC14
• Vector: pLenti-C-mGFP
• ACCN: NM_002638
• ORF Size: 351 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203136).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_002638.2, NP_002629.1
• RefSeq Size: 579 bp
• RefSeq ORF: 354 bp
• Locus ID: 5266
• Cytogenetics: 20q13.12
• Protein Families: Secreted Protein, Transmembrane
• MW: 12.3 kDa
• Gene Summary: 'This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines. [provided by RefSeq, Oct 2014]'