TPP1 (NM_000391) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC204471L2V

Lenti ORF particles, TPP1 (mGFP-tagged) - Human tripeptidyl peptidase I (TPP1), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: TPP1
• Synonyms: CLN2; GIG1; LPIC; SCAR7; TPP-1
• Vector: pLenti-C-mGFP
• ACCN: NM_000391
• ORF Size: 1689 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204471).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000391.3, NP_000382.3
• RefSeq Size: 3540 bp
• RefSeq ORF: 1692 bp
• Locus ID: 1200
• Cytogenetics: 11p15.4
• Protein Families: Protease
• Protein Pathways: Lysosome
• MW: 61.2 kDa
• Gene Summary: 'This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008]'