RRM2 (NM_001034) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC205718L1V

Lenti ORF particles, RRM2 (Myc-DDK tagged) - Human ribonucleotide reductase M2 (RRM2), transcript variant 2, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: RRM2
• Synonyms: C2orf48; R2; RR2; RR2M
• Vector: pLenti-C-Myc-DDK
• ACCN: NM_001034
• ORF Size: 1167 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC205718).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001034.1, NP_001025.1
• RefSeq Size: 2500 bp
• RefSeq ORF: 1170 bp
• Locus ID: 6241
• Cytogenetics: 2p25.1
• Domains: ribonuc_red_sm
• Protein Families: Druggable Genome
• Protein Pathways: Glutathione metabolism, Metabolic pathways, p53 signaling pathway, Purine metabolism, Pyrimidine metabolism
• MW: 44.7 kDa
• Gene Summary: 'This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Sep 2009]'