CysLT1 (CYSLTR1) (NM_006639) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC207763L2V

  • LentiORF®

Lenti ORF particles, CYSLTR1 (mGFP-tagged) - Human cysteinyl leukotriene receptor 1 (CYSLTR1), 200ul, >10^7 TU/mL

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USD 820.00

6 Weeks*

Size
    • 200 ul
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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol CYSLTR1
Synonyms CYSLT1; CYSLT1R; CYSLTR; HMTMF81
Vector pLenti-C-mGFP
ACCN NM_006639
ORF Size 1011 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC207763).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_006639.2, NP_006630.1
RefSeq Size 1537
RefSeq ORF 1014
Locus ID 10800
Domains 7tm_1
Protein Families Druggable Genome, GPCR, Transmembrane
Protein Pathways Calcium signaling pathway, Neuroactive ligand-receptor interaction
MW 38.4 kDa
Gene Summary This gene encodes a member of the G-protein coupled receptor 1 family. The encoded protein is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.