c-Myb (MYB) (NM_005375) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC209061L3V

Lenti ORF particles, MYB (Myc-DDK tagged) - Human v-myb myeloblastosis viral oncogene homolog (avian) (MYB), transcript variant 2, 200ul, >10^7 TU/mL

Product Images

RC209061L3 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC209061L3V particle to overexpress human MYB-Myc-DDK fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: MYB
• Synonyms: c-myb; c-myb_CDS; Cmyb; efg
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_005375
• ORF Size: 1920 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209061).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005375.2, NP_005366.2
• RefSeq Size: 3342 bp
• RefSeq ORF: 1923 bp
• Locus ID: 4602
• UniProt ID: P10242, Q708E9
• Cytogenetics: 6q23.3
• Domains: myb_DNA-binding
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transcription Factors
• MW: 72.2 kDa
• Gene Summary: 'This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]'