LLGL2 (NM_001031803) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC209559L3V

Lenti ORF particles, LLGL2 (Myc-DDK tagged) - Human lethal giant larvae homolog 2 (Drosophila) (LLGL2), transcript variant 3, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Symbol: LLGL2
• Synonyms: HGL; Hugl-2; LGL2
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• ACCN: NM_001031803
• ORF Size: 3060 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209559).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_001031803.1, NP_001026973.1
• RefSeq Size: 3590 bp
• RefSeq ORF: 3063 bp
• Locus ID: 3993
• Cytogenetics: 17q25.1
• Protein Families: Druggable Genome
• Protein Pathways: Tight junction
• MW: 113.4 kDa
• Gene Summary: 'The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]'