PI 3 Kinase regulatory subunit 4 (PIK3R4) (NM_014602) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC210308L4V

Lenti ORF particles, PIK3R4 (mGFP-tagged) - Human phosphoinositide-3-kinase, regulatory subunit 4 (PIK3R4), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: PIK3R4
• Synonyms: p150; VPS15
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_014602
• ORF Size: 4074 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC210308).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_014602.1, NP_055417.1
• RefSeq Size: 5078
• RefSeq ORF: 4077
• Locus ID: 30849
• Domains: pkinase, WD40, S_TKc
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Regulation of autophagy
• MW: 153.1 kDa
• Gene Summary: Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123). [UniProtKB/Swiss-Prot Function]