Melatonin Receptor 1A (MTNR1A) (NM_005958) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC210385L4V

Lenti ORF particles, MTNR1A (mGFP-tagged) - Human melatonin receptor 1A (MTNR1A), 200ul, >10^7 TU/mL

Product Images

RC210385L4 was used to prepare Lentiviral particles using TR30037 packaging kit. HEK293T cells were transduced with RC210385L4V particle to overexpress human MTNR1A-mGFP fusion protein.

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: MTNR1A
• Synonyms: MEL-1A-R; MT1
• Mammalian Cell Selection: Puromycin
• Vector: pLenti-C-mGFP-P2A-Puro
• ACCN: NM_005958
• ORF Size: 1050 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC210385).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_005958.3, NP_005949.1
• RefSeq Size: 1105 bp
• RefSeq ORF: 1053 bp
• Locus ID: 4543
• UniProt ID: P48039
• Cytogenetics: 4q35.2
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• MW: 39.4 kDa
• Gene Summary: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin. [provided by RefSeq, Jul 2008]