HNF1 alpha (HNF1A) (NM_000545) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC211201L2V

Lenti ORF particles, HNF1A (mGFP-tagged) - Human HNF1 homeobox A (HNF1A), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: HNF1A
• Synonyms: HNF-1A; HNF1; HNF4A; IDDM20; LFB1; MODY3; TCF-1; TCF1
• Vector: pLenti-C-mGFP
• ACCN: NM_000545
• ORF Size: 1893 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC211201).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_000545.3, NP_000536.3
• RefSeq Size: 3249 bp
• RefSeq ORF: 1896 bp
• Locus ID: 6927
• Cytogenetics: 12q24.31
• Protein Families: Adult stem cells, Druggable Genome, ES Cell Differentiation/IPS, Transcription Factors
• Protein Pathways: Maturity onset diabetes of the young
• MW: 67.2 kDa
• Gene Summary: 'The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]'