c Rel (REL) (NM_002908) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC211878L2V

Lenti ORF particles, REL (mGFP-tagged)-Human v-rel reticuloendotheliosis viral oncogene homolog (avian) (REL), 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: REL
• Synonyms: C-Rel
• Vector: pLenti-C-mGFP
• ACCN: NM_002908
• ORF Size: 1857 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC211878).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_002908.2, NP_002899.1
• RefSeq Size: 2592 bp
• RefSeq ORF: 1860 bp
• Locus ID: 5966
• Cytogenetics: 2p16.1
• Domains: RHD, IPT
• Protein Families: Druggable Genome, Transcription Factors
• MW: 68.5 kDa
• Gene Summary: 'This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]'