PYHIN1 (NM_152501) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC213494L2V

Lenti ORF particles, PYHIN1 (mGFP-tagged) - Human pyrin and HIN domain family, member 1 (PYHIN1), transcript variant a1, 200ul, >10^7 TU/mL

Specifications

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Symbol: PYHIN1
• Synonyms: IFIX
• Vector: pLenti-C-mGFP
• ACCN: NM_152501
• ORF Size: 1476 bp
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC213494).
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_152501.2, NP_689714.2
• RefSeq Size: 1749
• RefSeq ORF: 1479
• Locus ID: 149628
• MW: 54.9 kDa
• Gene Summary: The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2, which leads to stabilization of p53/TP53. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]