DVL1 (NM_004421) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC217691L3V
- LentiORF®
Lenti ORF particles, DVL1 (Myc-DDK tagged) - Human dishevelled, dsh homolog 1 (Drosophila) (DVL1), 200ul, >10^7 TU/mL
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | Myc-DDK |
Symbol | DVL1 |
Synonyms | DRS2; DVL; DVL1L1; DVL1P1 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_004421 |
ORF Size | 2010 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC217691).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_004421.2, NP_004412.2 |
RefSeq Size | 2941 bp |
RefSeq ORF | 2013 bp |
Locus ID | 1855 |
Cytogenetics | 1p36.33 |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
Protein Pathways | Basal cell carcinoma, Colorectal cancer, Melanogenesis, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway |
MW | 72.7 kDa |
Gene Summary | 'DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. [provided by RefSeq, Jul 2008]' |
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