AKAP5 (NM_004857) Human Tagged ORF Clone Lentiviral Particle

CAT#: RC221314L2V

  • LentiORF®

Lenti ORF particles, AKAP5 (mGFP-tagged) - Human A kinase (PRKA) anchor protein 5 (AKAP5), 200ul, >10^7 TU/mL


Biosafety Sheet

USD 820.00

3 Weeks*

Size
    • 200 ul

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Specifications

Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Symbol AKAP5
Synonyms AKAP75; AKAP79; H21
Vector pLenti-C-mGFP
ACCN NM_004857
ORF Size 1281 bp
Sequence Data
The ORF insert of this clone is exactly the same as(RC221314).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_004857.2, NP_004848.2
RefSeq Size 2601
RefSeq ORF 1284
Locus ID 9495
Domains PkinA_anch
Protein Families Druggable Genome
MW 46.9 kDa
Gene Summary The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. [provided by RefSeq, Jul 2008]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.