Human ABCF1 activation kit by CRISPRa

CAT#: GA100015

ABCF1 CRISPRa kit - CRISPR gene activation of human ATP binding cassette subfamily F member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ABCF1
• Locus ID: 23
• Kit Components:

  GA100015G1, ABCF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100015G2, ABCF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100015G3, ABCF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001025091, NM_001090
• Synonyms: ABC27; ABC50
• Summary: 'The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. [provided by RefSeq, Jul 2008]'