Human ACADL activation kit by CRISPRa

CAT#: GA100025

ACADL CRISPRa kit - CRISPR gene activation of human acyl-CoA dehydrogenase long chain

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ACADL
• Locus ID: 33
• Kit Components:

  GA100025G1, ACADL gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100025G2, ACADL gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100025G3, ACADL gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001608
• Synonyms: ACAD4; LCAD
• Summary: 'The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq, Jul 2008]'