Human ADAM8 activation kit by CRISPRa

CAT#: GA100065

ADAM8 CRISPRa kit - CRISPR gene activation of human ADAM metallopeptidase domain 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ADAM8
• Locus ID: 101
• Kit Components:

  GA100065G1, ADAM8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100065G2, ADAM8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100065G3, ADAM8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001109, NM_001164489, NM_001164490
• Synonyms: CD156; CD156a; MS2
• Summary: 'This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009]'