Human AP2B1 activation kit by CRISPRa

CAT#: GA100116

AP2B1 CRISPRa kit - CRISPR gene activation of human adaptor related protein complex 2 subunit beta 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AP2B1
• Locus ID: 163
• Kit Components:

  GA100116G1, AP2B1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100116G2, AP2B1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100116G3, AP2B1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001030006, NM_001282
• Synonyms: ADTB2; AP2-BETA; AP105B; CLAPB1
• Summary: 'The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'