Human 15 Lipoxygenase 2 (ALOX15B) activation kit by CRISPRa

CAT#: GA100171

ALOX15B CRISPRa kit - CRISPR gene activation of human arachidonate 15-lipoxygenase type B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ALOX15B
• Locus ID: 247
• Kit Components:

  GA100171G1, 15 Lipoxygenase 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100171G2, 15 Lipoxygenase 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100171G3, 15 Lipoxygenase 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001039130, NM_001039131, NM_001141
• Synonyms: 15-LOX-2
• Summary: 'This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]'