Human Salivary alpha amylase (AMY1A) activation kit by CRISPRa

CAT#: GA100191

AMY1A CRISPRa kit - CRISPR gene activation of human amylase alpha 1A (salivary)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AMY1A
• Locus ID: 276
• Kit Components:

  GA100191G1, Salivary alpha amylase gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100191G2, Salivary alpha amylase gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100191G3, Salivary alpha amylase gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001008221, NM_004038
• Synonyms: AMY1
• Summary: 'Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the salivary gland. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]'