Human APOBEC1 activation kit by CRISPRa

CAT#: GA100240

APOBEC1 CRISPRa kit - CRISPR gene activation of human apolipoprotein B mRNA editing enzyme catalytic subunit 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: APOBEC1
• Locus ID: 339
• Kit Components:

  GA100240G1, APOBEC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100240G2, APOBEC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100240G3, APOBEC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001304566, NM_001644, NM_005889
• Synonyms: APOBEC-1; BEDP; CDAR1; HEPR
• Summary: This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2015]