Human ARF6 activation kit by CRISPRa

CAT#: GA100274

ARF6 CRISPRa kit - CRISPR gene activation of human ADP ribosylation factor 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ARF6
• Locus ID: 382
• Kit Components:

  GA100274G1, ARF6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100274G2, ARF6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100274G3, ARF6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001663
• Synonyms: DKFZp564M0264
• Summary: 'This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. [provided by RefSeq, Jul 2008]'