Human RND3 activation kit by CRISPRa

CAT#: GA100280

RND3 CRISPRa kit - CRISPR gene activation of human Rho family GTPase 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RND3
• Locus ID: 390
• Kit Components:

  GA100280G1, RND3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100280G2, RND3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100280G3, RND3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001254738, NM_005168
• Synonyms: ARHE; memB; Rho8; RhoE
• Summary: 'This gene encodes a protein which is a member of the small GTPase protein superfamily. The encoded protein binds only GTP but has no GTPase activity, and appears to act as a negative regulator of cytoskeletal organization leading to loss of adhesion. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]'