Human ASMT activation kit by CRISPRa

CAT#: GA100316

ASMT CRISPRa kit - CRISPR gene activation of human acetylserotonin O-methyltransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ASMT
• Locus ID: 438
• Kit Components:

  GA100316G1, ASMT gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100316G2, ASMT gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100316G3, ASMT gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001171038, NM_001171039, NM_004043
• Synonyms: ASMTY; HIOMT; HIOMTY
• Summary: This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2010]