Human ATF3 activation kit by CRISPRa

CAT#: GA100326

ATF3 CRISPRa kit - CRISPR gene activation of human activating transcription factor 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ATF3
• Locus ID: 467
• Kit Components:

  GA100326G1, ATF3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100326G2, ATF3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100326G3, ATF3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001030287, NM_001040619, NM_001206484, NM_001206485, NM_001206486, NM_001206488, NM_001674, NM_004024
• Synonyms: FLJ41705
• Summary: 'This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes. [provided by RefSeq, Apr 2011]'