Human BHMT activation kit by CRISPRa

CAT#: GA100432

BHMT CRISPRa kit - CRISPR gene activation of human betaine--homocysteine S-methyltransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BHMT
• Locus ID: 635
• Kit Components:

  GA100432G1, BHMT gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100432G2, BHMT gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100432G3, BHMT gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001713
• Synonyms: BHMT1; HEL-S-61p
• Summary: 'This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed. [provided by RefSeq, Jul 2008]'