Human BLK activation kit by CRISPRa

CAT#: GA100437

BLK CRISPRa kit - CRISPR gene activation of human BLK proto-oncogene, Src family tyrosine kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BLK
• Locus ID: 640
• Kit Components:

  GA100437G1, BLK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100437G2, BLK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100437G3, BLK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001715, NM_001330465
• Synonyms: MODY11
• Summary: 'This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010]'