Human TIS11B (ZFP36L1) activation kit by CRISPRa

CAT#: GA100472

ZFP36L1 CRISPRa kit - CRISPR gene activation of human ZFP36 ring finger protein like 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ZFP36L1
• Locus ID: 677
• Kit Components:

  GA100472G1, TIS11B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100472G2, TIS11B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100472G3, TIS11B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001244698, NM_001244701, NM_004926
• Synonyms: Berg36; BRF1; cMG1; ERF-1; ERF1; RNF162B; TIS11B
• Summary: 'This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]'