Human C4BPA activation kit by CRISPRa

CAT#: GA100502

C4BPA CRISPRa kit - CRISPR gene activation of human complement component 4 binding protein alpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: C4BPA
• Locus ID: 722
• Kit Components:

  GA100502G1, C4BPA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100502G2, C4BPA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100502G3, C4BPA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000715
• Synonyms: C4BP; PRP
• Summary: This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. Along with a single, unique beta-chain, seven identical alpha-chains encoded by this gene assemble into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Two pseudogenes of this gene are also found in the cluster. [provided by RefSeq, Jul 2008]