Human Carbonic Anhydrase II (CA2) activation kit by CRISPRa

CAT#: GA100528

CA2 CRISPRa kit - CRISPR gene activation of human carbonic anhydrase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CA2
• Locus ID: 760
• Kit Components:

  GA100528G1, Carbonic Anhydrase II gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100528G2, Carbonic Anhydrase II gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100528G3, Carbonic Anhydrase II gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000067, NM_001293675
• Synonyms: CA-II; CAC; CAII; Car2; HEL-76; HEL-S-282
• Summary: 'The protein encoded by this gene is one of several isozymes of carbonic anhydrase, which catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]'