Human CACNA1B activation kit by CRISPRa

CAT#: GA100539

CACNA1B CRISPRa kit - CRISPR gene activation of human calcium voltage-gated channel subunit alpha1 B

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CACNA1B
• Locus ID: 774
• Kit Components:

  GA100539G1, CACNA1B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100539G2, CACNA1B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100539G3, CACNA1B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000718, NM_001243812
• Synonyms: BIII; CACNL1A5; CACNN; Cav2.2
• Summary: 'The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]'