Human SLC25A20 activation kit by CRISPRa

CAT#: GA100552

SLC25A20 CRISPRa kit - CRISPR gene activation of human solute carrier family 25 member 20

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC25A20
• Locus ID: 788
• Kit Components:

  GA100552G1, SLC25A20 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100552G2, SLC25A20 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100552G3, SLC25A20 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000387
• Synonyms: CAC; CACT
• Summary: This gene product is one of several closely related mitochondrial-membrane carrier proteins that shuttle substrates between cytosol and the intramitochondrial matrix space. This protein mediates the transport of acylcarnitines into mitochondrial matrix for their oxidation by the mitochondrial fatty acid-oxidation pathway. Mutations in this gene are associated with carnitine-acylcarnitine translocase deficiency, which can cause a variety of pathological conditions such as hypoglycemia, cardiac arrest, hepatomegaly, hepatic dysfunction and muscle weakness, and is usually lethal in new born and infants. [provided by RefSeq, Jul 2008]