Human Calcitonin receptor (CALCR) activation kit by CRISPRa

CAT#: GA100559

CALCR CRISPRa kit - CRISPR gene activation of human calcitonin receptor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CALCR
• Locus ID: 799
• Kit Components:

  GA100559G1, Calcitonin receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100559G2, Calcitonin receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100559G3, Calcitonin receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001164737, NM_001164738, NM_001742
• Synonyms: CRT; CT-R; CTR; CTR1
• Summary: 'This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]'