Human CBS activation kit by CRISPRa

CAT#: GA100617

CBS CRISPRa kit - CRISPR gene activation of human cystathionine-beta-synthase

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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

Product Images

Frequently bought together (2)
Rabbit Polyclonal antibody to CBS (cystathionine-beta-synthase)
    • 100 ul

USD 415.00


qSTAR qPCR primer pairs against Homo sapiens gene CBS
    • 200 reactions

USD 120.00

Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol CBS
Locus ID 875
Kit Components

GA100617G1, CBS gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA100617G2, CBS gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA100617G3, CBS gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000071, NM_001178008, NM_001178009, NM_001320298, NM_001321072
Synonyms HIP4
Summary 'The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2016]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.