Human Cyclin G2 (CCNG2) activation kit by CRISPRa

CAT#: GA100632

CCNG2 CRISPRa kit - CRISPR gene activation of human cyclin G2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CCNG2
• Locus ID: 901
• Kit Components:

  GA100632G1, Cyclin G2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100632G2, Cyclin G2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100632G3, Cyclin G2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004354
• Synonyms: cyclin G2; OTTHUMP00000160592
• Summary: 'The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle. [provided by RefSeq, Jul 2008]'