Human CD48 activation kit by CRISPRa

CAT#: GA100684

CD48 CRISPRa kit - CRISPR gene activation of human CD48 molecule

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CD48
• Locus ID: 962
• Kit Components:

  GA100684G1, CD48 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100684G2, CD48 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100684G3, CD48 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001256030, NM_001778
• Synonyms: BCM1; BLAST; BLAST1; hCD48; mCD48; MEM-102; SLAMF2
• Summary: 'This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]'