Human CEBP Beta (CEBPB) activation kit by CRISPRa

CAT#: GA100758

CEBPB CRISPRa kit - CRISPR gene activation of human CCAAT enhancer binding protein beta

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CEBPB
• Locus ID: 1051
• Kit Components:

  GA100758G1, CEBP Beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100758G2, CEBP Beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100758G3, CEBP Beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001285878, NM_001285879, NM_005194
• Synonyms: C/EBP-beta; IL6DBP; NF-IL6; TCF5
• Summary: 'This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions. [provided by RefSeq, Oct 2013]'