Human CEBP gamma (CEBPG) activation kit by CRISPRa

CAT#: GA100761

CEBPG CRISPRa kit - CRISPR gene activation of human CCAAT enhancer binding protein gamma

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CEBPG
• Locus ID: 1054
• Kit Components:

  GA100761G1, CEBP gamma gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100761G2, CEBP gamma gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100761G3, CEBP gamma gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001252296, NM_001806
• Synonyms: GPE1BP; IG/EBP-1
• Summary: The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins, C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that form homodimers and that form heterodimers with each other. CCAAT/enhancer binding protein gamma may cooperate with Fos to bind PRE-I enhancer elements. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2011]