Human CLIC2 activation kit by CRISPRa

CAT#: GA100853

CLIC2 CRISPRa kit - CRISPR gene activation of human chloride intracellular channel 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CLIC2
• Locus ID: 1193
• Kit Components:

  GA100853G1, CLIC2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100853G2, CLIC2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100853G3, CLIC2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001289
• Synonyms: CLIC2b; MRXS32; XAP121
• Summary: 'This gene encodes a chloride intracellular channel protein. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. This protein plays a role in inhibiting the function of ryanodine receptor 2. A mutation in this gene is the cause of an X-linked form of cognitive disability. [provided by RefSeq, Jul 2017]'