Human CCR4 activation kit by CRISPRa

CAT#: GA100869

CCR4 CRISPRa kit - CRISPR gene activation of human C-C motif chemokine receptor 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CCR4
• Locus ID: 1233
• Kit Components:

  GA100869G1, CCR4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100869G2, CCR4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100869G3, CCR4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005508
• Synonyms: CC-CKR-4; CD194; ChemR13; CKR4; CMKBR4; HGCN:14099; K5-5
• Summary: 'The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008]'