Human Cytochrome C Oxidase subunit VIb (COX6B1) activation kit by CRISPRa

CAT#: GA100936

COX6B1 CRISPRa kit - CRISPR gene activation of human cytochrome c oxidase subunit 6B1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: COX6B1
• Locus ID: 1340
• Kit Components:

  GA100936G1, Cytochrome C Oxidase subunit VIb gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100936G2, Cytochrome C Oxidase subunit VIb gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100936G3, Cytochrome C Oxidase subunit VIb gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001863
• Synonyms: COX6B; COXG; COXVIb1
• Summary: 'Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively. [provided by RefSeq, Jan 2010]'