Human CRABP2 activation kit by CRISPRa

CAT#: GA100969

CRABP2 CRISPRa kit - CRISPR gene activation of human cellular retinoic acid binding protein 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CRABP2
• Locus ID: 1382
• Kit Components:

  GA100969G1, CRABP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA100969G2, CRABP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA100969G3, CRABP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001199723, NM_001878
• Synonyms: CRABP-II; RBP6
• Summary: 'This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2010]'