Human Mitochondrial dicarboxylate carrier (SLC25A10) activation kit by CRISPRa

CAT#: GA101036

SLC25A10 CRISPRa kit - CRISPR gene activation of human solute carrier family 25 member 10

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC25A10
• Locus ID: 1468
• Kit Components:

  GA101036G1, SLC25A10 gRNA vector 1 in pCas-Guide-CRISPRa

  GA101036G2, SLC25A10 gRNA vector 2 in pCas-Guide-CRISPRa

  GA101036G3, SLC25A10 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001270888, NM_001270953, NM_012140
• Synonyms: DIC
• Summary: This gene encodes a member of a family of proteins that translocate small metabolites across the mitochondrial membrane. The encoded protein exchanges dicarboxylates, such as malate and succinate, for phosphate, sulfate, and other small molecules, thereby providing substrates for metabolic processes including the Krebs cycle and fatty acid synthesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]