Human Cathepsin H (CTSH) activation kit by CRISPRa

CAT#: GA101070

CTSH CRISPRa kit - CRISPR gene activation of human cathepsin H

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CTSH
• Locus ID: 1512
• Kit Components:

  GA101070G1, Cathepsin H gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101070G2, Cathepsin H gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101070G3, Cathepsin H gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001319137, NM_004390, NM_148979
• Synonyms: ACC-4; ACC-5; ACC4; ACC5; CPSB
• Summary: 'The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]'