Human DACH1 activation kit by CRISPRa

CAT#: GA101126

DACH1 CRISPRa kit - CRISPR gene activation of human dachshund family transcription factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DACH1
• Locus ID: 1602
• Kit Components:

  GA101126G1, DACH1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101126G2, DACH1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101126G3, DACH1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004392, NM_080759, NM_080760, NM_001366712
• Synonyms: DACH
• Summary: 'This gene encodes a chromatin-associated protein that associates with other DNA-binding transcription factors to regulate gene expression and cell fate determination during development. The protein contains a Ski domain that is highly conserved from Drosophila to human. Expression of this gene is lost in some forms of metastatic cancer, and is correlated with poor prognosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]'