Human SAP102 (DLG3) activation kit by CRISPRa

CAT#: GA101210

DLG3 CRISPRa kit - CRISPR gene activation of human discs large MAGUK scaffold protein 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DLG3
• Locus ID: 1741
• Kit Components:

  GA101210G1, SAP102 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101210G2, SAP102 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101210G3, SAP102 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001166278, NM_020730, NM_021120
• Synonyms: MRX; MRX90; NEDLG; PPP1R82; SAP102; XLMR
• Summary: 'This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]'