Human OVCA1 (DPH1) activation kit by CRISPRa

CAT#: GA101254

DPH1 CRISPRa kit - CRISPR gene activation of human diphthamide biosynthesis 1

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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Frequently bought together (2)
Rabbit Polyclonal Anti-DPH1 Antibody
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qSTAR qPCR primer pairs against Homo sapiens gene DPH1
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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol DPH1
Locus ID 1801
Kit Components

GA101254G1, OVCA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA101254G2, OVCA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA101254G3, OVCA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001383, NM_001346574, NM_001346575, NM_001346576, NR_144474, NR_144475, NR_144476
Synonyms DPH2L; DPH2L1; OVCA1
Summary 'The protein encoded by this gene is an enzyme involved in the biosynthesis of diphthamide, a modified histidine found only in elongation factor-2 (EEF2). Diphthamide residues in EEF2 are targeted for ADP-ribosylation by diphtheria toxin and Pseudomonas exotoxin A. Defects in this gene have been associated with both ovarian cancer and autosomal recessive intellectual disability with short stature, craniofacial, and ectodermal anomalies. [provided by RefSeq, Oct 2016]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.