Human SLC26A3 activation kit by CRISPRa

CAT#: GA101264

SLC26A3 CRISPRa kit - CRISPR gene activation of human solute carrier family 26 member 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC26A3
• Locus ID: 1811
• Kit Components:

  GA101264G1, SLC26A3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA101264G2, SLC26A3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA101264G3, SLC26A3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_000111
• Synonyms: CLD; DRA
• Summary: The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea. [provided by RefSeq, Oct 2008]