Human E2F6 activation kit by CRISPRa

CAT#: GA101313

E2F6 CRISPRa kit - CRISPR gene activation of human E2F transcription factor 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: E2F6
• Locus ID: 1876
• Kit Components:

  GA101313G1, E2F6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101313G2, E2F6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101313G3, E2F6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278275, NM_001278276, NM_001278277, NM_001278278, NM_001952, NM_198256, NM_198257, NM_198258, NM_198325, NM_212540, NR_003092, NR_003093, NR_003094, NR_003095, NR_103490
• Synonyms: E2F-6
• Summary: 'This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene on chromosomes 22 and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]'