Human PHC1 activation kit by CRISPRa

CAT#: GA101332

PHC1 CRISPRa kit - CRISPR gene activation of human polyhomeotic homolog 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: PHC1
• Locus ID: 1911
• Kit Components:

  GA101332G1, PHC1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA101332G2, PHC1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA101332G3, PHC1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_004426
• Synonyms: EDR1; HPH1; MCPH11; RAE28
• Summary: 'This gene is a homolog of the Drosophila polyhomeotic gene, which is a member of the Polycomb group of genes. The gene product is a component of a multimeric protein complex that contains EDR2 and the vertebrate Polycomb protein BMH1. The gene product, the EDR2 protein, and the Drosophila polyhomeotic protein share 2 highly conserved domains, named homology domains I and II. These domains are involved in protein-protein interactions and may mediate heterodimerization of the protein encoded by this gene and the EDR2 protein. [provided by RefSeq, Jul 2008]'